Gelatin vs vegan (HPMC) capsules: which suits your supplement?

Gelatin vs HPMC (vegan) capsule shells for supplements: what each is made from, how they behave with different fills, and what to consider for your product.

Hard capsule shells are usually made from gelatin or from hypromellose (HPMC), a plant-derived cellulose. Both work well; the right choice depends on your fill, your customers and your cost.

Gelatin capsules

Made from animal-derived gelatin. They are widely available and usually the lower-cost option. Gelatin shells hold some moisture, which can matter for fills that are sensitive to moisture.

HPMC (vegan) capsules

Made from plant cellulose, so they suit vegetarian and vegan products. They hold less moisture than gelatin, which can suit moisture-sensitive fills. They usually cost more than gelatin.

Other things to consider

  • Dietary or religious requirements: the source and certification of the shell matter

  • Fill properties: how the powder flows and how much fits in each capsule size

  • Your label: shell type is part of the product specification

Talk to us about which shell types and sizes suit your product. See capsule filling.

This guide is general information only. It is not regulatory or legal advice, and requirements change. Check current requirements with the TGA or a qualified regulatory consultant before making decisions about your product.

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The information on this website is general in nature. It is not regulatory, legal or medical advice. DB Pharmaceuticals manufactures products to the specifications approved by each brand owner, who is responsible for their product's regulatory status, claims and labelling.